Polyphenols: immunonutrients tipping the balance of immunometabolism in chronic diseases Mounting evidence progressively appreciates the vital interplay between immunity and metabolism in a wide array of immunometabolic chronic disorders, both autoimmune and...

Image: Summary of fndings. AMPK phosphorylation was lowered in the colon and hypothalamus after High Sugar High Fat (HSHF) intake Obesogenic diets (ODs) can affect AMPK activation in several sites as the colon, liver, and hypothalamus. OD intake can impair the...

Featured Image sourced from "Brain-gut-liver interactions across the spectrum of insulin resistance in metabolic fatty liver disease," World J Gastroenterol. 2021 Aug 14; 27(30): 4999–5018. Published online 2021 Aug 14. doi: 10.3748/wjg.v27.i30.4999 While glucose...

Avenues within the gut-liver-brain axis linking chronic liver disease and symptoms Symptoms of fatigue, social withdrawal and mood disturbances are commonly encountered in patients with chronic liver disease and have a detrimental effect on patient quality of life....

The gut-liver-brain axis is a three-way highway of information interaction among the gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough progress has been made in this axis, mainly through understanding its formation mechanism and...

What is the gut-brain-liver axis? The axis connecting the gut, brain, and liver, which is otherwise known as the gut-brain-liver axis, is a three-way interaction that has recently garnered increasing scientific interest. Over the last two decades, researchers have...

In the fevered world of diet and nutrition, the past year has been dominated by heated arguments about the evils (or not) of ultra-processed foods. These have not just been confined to the media but have, unusually, engendered equally fractious debate in academic...

Ultra-processed foods: largest ever review shows many ill effects on health – how to understand the evidence Ultra-processed foods, such as cereals and fizzy drinks, have been linked to 32 harmful health effects, according to the largest review of the evidence to...

Move to sustainable food systems could bring $10tn benefits a year, study finds Existing production destroys more value than it creates due to medical and environmental costs, researchers say A shift towards a more sustainable global food system could create up to...

Most everyone thinks obesity is about calories, known as the Energy Balance Model (EBM).   But that doesn’t explain why certain foods cause more obesity, it doesn’t take the role of the microbiome into account, and it doesn’t explain why certain chemicals cause...