What is the gut-brain-liver axis?
The axis connecting the gut, brain, and liver, which is otherwise known as the gut-brain-liver axis, is a three-way interaction that has recently garnered increasing scientific interest. Over the last two decades, researchers have achieved significant progress in exploring gut-brain-liver communication by better understanding its development process and expanding therapeutic options. Interventions based on the gut-brain-liver connection could facilitate personalized treatment.
Mechanisms linking the gut and liver
Communication between the liver and gastrointestinal tract involves a complex network of interconnected pathways that play a critical role in a variety of diseases, including chronic-type hepatitis B virus (HBV), HCV, non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD), and hepatocellular carcinoma (HCC).
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